Medicare may cover the costs of a purified protein derivative (PPD) test if a person has symptoms or has been exposed to tuberculosis (TB). If not, Medicare will likely deny coverage as it would consider it a screening only.

According to the World Health Organization (WHO)Trusted Source, TB was responsible for the deaths of 1.25 million people worldwide in 2023.

Although it is a highly contagious health condition, it is fairly rare in the United States. If people do develop the condition, they often show no symptoms.

A PPD skin test, also sometimes called a tuberculin skin test (TST)Trusted Source, can determine if a person has TB. If a healthcare team decides to perform the test to diagnose TB following symptoms, Medicare Part B would cover eligible costs.

In 2025, the Part B deductible will be $257. Once a person pays this amount, Medicare covers 80% of costs, but it may also cover diagnostic lab tests in full.

A person with Original Medicare (parts A and B) can contact Medicare directly to confirm coverage. People with Medicare Advantage plans can contact their plan provider, as coverage and out-of-pocket expenses can differ by insurer, plan, and location.

This test involves a doctor or healthcare professional injecting a fluid called tuberculin beneath a person’s skin. It may also be called a TST.

This test will require two visits. During the first visit, an individual will receive the injection. During the second, a doctor or healthcare professional will examine the skin for a reaction. There is usually a period of 2 to 3 daysTrusted Source between the two appointments.

A healthcare team may suggest a blood test for TBTrusted Source. This is because people who have received a TB vaccination may show a false-positive reaction to the PPD test.

A person may consider getting a PPD skin testTrusted Source if they work in healthcare, as all healthcare workers must receive routine TB screening.

Individuals should also consider a PPD skin test if:

  • they have come into contact with someone with TB
  • they take immunosuppressive drugs and have a weakened immune system
  • they have specific health conditions, such as cancer or HIV

If a person has TB, they may develop symptoms in the lungsTrusted Source, such as:

  • coughing for more than 3 weeks
  • chest pain
  • coughing up phlegm or blood

If an individual has active TB, they may also experience other symptoms affecting the whole body, including:

  • fatigue
  • weight loss
  • night sweats
  • chills
  • fever